The Best Supplements 4 Fibromyalgia & Arthritis | FTKWellness Tips
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May is Fibromyalgia Awareness Month. With fibromyalgia classified under—and impacted by—various arthritis-related conditions, Freedom To Know Wellness would like to close the month by highlighting highly beneficial supplements, including supplement formulas that support the many symptoms associated with fibromyalgia and arthritis, to assist you in your wellness journey.
As a Canadian company, Freedom To Know Wellness is proud to feature Canadian-owned and Canadian-operated companies in our recommended supplement formulas.
***Consult your practitioner before starting any supplements.
🧠 Supplements for Fibromyalgia and Arthritis (Alphabetical Order)
Benefits listed under each supplement:
Chondroitin 🦴
Pain: Works with glucosamine to reduce joint inflammation and stiffness.
Note: Take in conjunction with Glucosomine as a combined supplement
Additional Recommendation: Swansea Sea Cucumber supplement as a combined supplement for joint care
Coenzyme Q10 (CoQ10)
Benefits:
Fatigue & Energy: Enhances mitochondrial function, boosting energy production.
Pain: May reduce muscle pain and tenderness.
Curcumin 🫚
Pain: Potent anti-inflammatory for joints and nerves.
Mood & Cognitive Support: May enhance brain-derived neurotrophic factor (BDNF) and reduce brain fog.
Digestive Enzymes 🧻
Digestive Health: Improves digestion and nutrient absorption, reducing IBS symptoms.
Fatigue & Energy: Enhances nutrient uptake for energy production.
D-Ribose
a natural sugar molecule has shown promise in reducing fibromyalgia symptoms.
may improve energy levels, sleep, and pain intensity
Prevent Chronic Fatigue
Essential Amino Acids 💪
Fatigue & Energy: Required for energy production and muscle repair.
Mood & Cognitive Support: Supports neurotransmitter synthesis.
Flaxseed Oil 🌱
Benefits:
Pain: Alleviates joint pain and stiffness.
Digestive Health: Supports digestive regularity.
Fatigue & Energy: Provides essential fatty acids that support energy metabolism.
Glucosamine 🍖💊
Pain: Supports cartilage health and reduces arthritis pain.
Hyaluronic Acid 💊🍖
Pain: Supports joint lubrication and reduces stiffness.
5-HTP (5-Hydroxytryptophan) 😴🙂💊
Sleep/Insomnia: Boosts serotonin production, which improves sleep quality — crucial for fibromyalgia symptom relief.
Mood & Cognitive Support: Helps reduce depression, anxiety, and "fibro fog" by increasing serotonin levels.
Pain Relief: Some studies suggest 5-HTP may help reduce the perception of pain in fibromyalgia by regulating neurotransmitters.
Inositol 🧠🙂
Mood & Cognitive Support: Reduces anxiety, depression, and brain fog.
Fatigue & Energy: Improves insulin sensitivity and stabilizes energy.
Pain: May reduce pain perception.
Inulin 🧻🧠
Digestive Health: Prebiotic that promotes the growth of beneficial gut bacteria.
Mood & Cognitive Support: Gut-brain axis support.
L-Creatine ⚡️💪🧠
Fatigue & Energy: Improves cellular ATP production and muscle strength.
Cognitive Support: May reduce mental fatigue.
L-Glutamine ⚡️🧻
Digestive Health: Repairs and supports gut lining (beneficial for leaky gut/IBS).
Fatigue & Energy: Fuels intestinal cells and muscles.
L-Taurine 💊⚡️
Pain: Neuroprotective; supports nerve and muscle function.
Fatigue & Energy: May reduce muscle fatigue.
Mood & Cognitive Support: Supports neurotransmitter balance and calms the nervous system.
Magnesium Bisglycinate 💪💊
Sleep: Promotes relaxation and deeper sleep.
Pain: Relieves muscle tension, spasms, and heart palpitations.
Mood & Cognitive Support: Helps reduce anxiety and supports mental clarity.
Fatigue & Energy: Supports energy metabolism.
**Bisglycinate strain is better for absorption and muscles relaxation
Malic Acid 💊
Fatigue & Energy: Enhances mitochondrial function and energy production.
Pain: May reduce muscle pain and tenderness.
Melatonin 😴
Benefits:
Sleep: Regulates sleep-wake cycles, improving sleep quality.
Mood & Cognitive Support: Reduces symptoms of depression and anxiety.
Note: Melatonin on its own is not always sufficient for a full night’s rest in fibromyalgia patients. A combined sleep supplement with herbs like Passion Flower, GABA, 5-HTP, Valerian Root, etc, aids in a better restful sleep. See “Combined Supplements” for recommended options.
MSM (Methylsulfonylmethane) 💊⚡️
Pain: Reduces joint/muscle pain and inflammation.
Fatigue & Energy: May improve energy and physical function.
Omega-3 Fatty Acids 🐠💊
Pain: Anti-inflammatory effects on joints and nerves.
Mood & Cognitive Support: Improves mood and mental clarity.
Fatigue & Energy: Reduces chronic fatigue by supporting mitochondrial membranes.
Omega 3-6-9 🝆💊
Benefits:
Pain: Reduces inflammation and joint pain.
Mood & Cognitive Support: Supports brain health and reduces cognitive decline.
Fatigue & Energy: Improves energy levels by supporting cellular function.
Potassium (Aspartate) 💪💊
Fatigue & Energy: Supports muscle and nerve function.
Pain: May reduce cramping and twitching.
Probiotics (e.g., Lactobacillus acidophilus) 🧻
Digestive Health: Helps balance gut flora and reduce IBS symptoms.
Mood & Cognitive Support: Gut-brain axis benefits can reduce brain fog, anxiety, and depression.
Immune Support: Strengthens gut-related immunity.
Rhodiola 🌿💊
Mood & Cognitive Support: Reduces brain fog, stress, and anxiety.
Fatigue & Energy: Adaptogen that boosts stamina and mental clarity.
Pain: Modulates stress-related inflammation.
Serrapeptase Enzyme ⚛️💊
Pain: Breaks down inflammatory proteins; may reduce swelling and discomfort.
Digestion: breaks down proteins into smaller components called amino acids.
Aid Scar Tissue & Anti-Inflammatory: aids the body’s response to injury, breaks down scar tissue and may prevent infection.
Note: Enzyme taken from the Silkworm 🐛
Tart Cherries 🍒 🧃💊
Pain: Reduces muscle soreness and joint inflammation.
Sleep: Natural source of melatonin; may help improve sleep.
Valerian Root 😴
Benefits:
Sleep: Increase levels of gamma-aminobutyric acid (GABA) in the brain to improve sleep quality by reducing anxiety, increasing relaxation.
Mood & Cognitive Support: May alleviate symptoms of depression.
Vitamin B12 / B-Complex ⚡️
Fatigue & Energy: Improves mitochondrial function and reduces fatigue.
Mood & Cognitive Support: Supports nerve health and reduces brain fog.
Pain: Helps repair nerve damage and reduce tingling/numbness.
Vitamin C 🍊💊
Pain: Antioxidant properties reduce joint pain and oxidative stress.
Fatigue & Energy: Supports adrenal function and collagen synthesis.
Vitamin D 🌞
Pain: Low levels linked to higher pain sensitivity.
Mood & Cognitive Support: May reduce depressive symptoms.
Fatigue & Energy: Supports cellular energy production.
Vitamin K2 🍖
Pain & Joint Health: Helps direct calcium to bones and teeth and away from joints and soft tissues, preventing calcification that can worsen arthritis symptoms.
Fatigue & Energy: Supports cardiovascular health, which may improve energy delivery to muscles.
Bone Support: Works synergistically with vitamin D to improve bone mineralization
Wobenzym ⚛️💊
Pain: A Systemic enzyme that reduces joint inflammation.
Fatigue & Energy: Enhances circulation and reduces inflammatory load.
🧪 Combined Formula Supplements
CALMAG 💪😴🇨🇦
Main Ingredients:
Calcium
Magnesium
Benefits:
Pain: Supports muscle relaxation and reduces cramps.
Sleep: Promotes restful sleep.
CanPrev Synergy B ⚡️🇨🇦
Main Ingredients:
Full-spectrum B vitamins in preferred forms (e.g., methylcobalamin, L-5-MTHF)
L-Theanine (200 mg daily)
Spirulina
Choline
Inositol
Benefits:
Fatigue & Energy: B vitamins support energy metabolism, reducing fatigue.
Mood & Cognitive Support: L-Theanine promotes relaxation without sedation, aiding in stress reduction and mental clarity.
Pain: Supports nerve health, potentially alleviating neuropathic pain.
Digestive Health: B vitamins aid in the metabolism of carbohydrates, fats, and proteins.
L-Theanine is an amino acid found in green tea leaves that temporarily produces mental relaxation without any sedating effects. It’s the perfect companion to a B-complex vitamin, enhancing its already stress-reducing and mood-enhancing properties. - Main Ingredient from CanPrev Synergy B
HMF Probiotic Formula 🧻🚽🇨🇦
Probiotic strains (e.g., L. acidophilus) – Gut-brain axis, IBS support, mood balance.
Isotonix OPC-3 (ORAC)
Main Ingredients:
Grape Seed Extract – Rich in oligomeric proanthocyanidins (OPCs), supports cardiovascular health and provides potent antioxidant protection.
Red Wine Extract – Contains resveratrol and OPCs, known for heart-health benefits and antioxidant properties.
Pine Bark Extract (Pycnogenol®) – A standardized extract from French maritime pine bark, offering potent antioxidant, anti-inflammatory, and circulation-boosting benefits.
Bilberry Extract – Rich in anthocyanins, supports eye health and protects against oxidative damage.
Citrus Bioflavonoids Extract – Promotes cardiovascular health and demonstrates anti-inflammatory activity.
Benefits:
Pain: Demonstrates anti-inflammatory activity and promotes joint health.
Mood & Cognitive Support: Enhances circulation, supporting brain oxygenation, which aids focus, memory, and clarity.
Digestive Health: Supports healthy blood glucose levels.
Fatigue & Energy: Improves energy levels by enhancing blood flow and oxygen delivery.
Immune Support: Combats free radicals, providing antioxidant protection.Medium+7shoplocal-usa+7nutraMetrix+7Medium
Note: Isotonix OPC-3 is delivered in an isotonic solution, allowing for rapid absorption and high bioavailability.
**American-owned with Canadian operations.
Mitochondrial NRG™ by Design for Health
Main Ingredients:
B Vitamins (B1, B2, B3, B6, B12)
Magnesium
Manganese
Creatine
L-Carnitine
Benefits:
Fatigue & Energy: Enhances mitochondrial function, boosting energy production.
Mood & Cognitive Support: Supports neurological function, reducing brain fog.
Pain: Improves muscle function and reduces discomfort.
**American-owned with Canadian operations.
Purica Recovery 3.0 🫚 🇨🇦
Main Ingredients:
Curcuma longa (Curcumin) – Pain, brain fog, inflammation
Curcuminoids (Bisdemethoxycurcumin) – Enhanced anti-inflammatory support
Hyaluronic Acid – Joint support
Chaga – Immune modulator, energy
Applephenon (Polyphenols) – Antioxidant, cognitive clarity
Magnesium – Sleep, pain, fatigue
Vitamin C – Antioxidant, pain relief
Sensoril® Ashwagandha – Stress, fatigue, cognitive support
Purica Recovery Extra Strength 🇨🇦
Main Ingredients:
Nutricol® (Bioflavonoids from Grape Seed and Green Tea)
Methylsulfonylmethane (MSM)
Glucosamine hydrochloride
Vitamin C
Betaine HCL
Magnesium
Vitamin E (natural d-alpha tocopheryl acetate)
Hyaluronic Acid
Benefits:
Pain: Relieves joint pain associated with osteoarthritis and supports joint health.
Fatigue & Energy: Enhances healing from surgery and rehab from injury, promoting overall energy.
Mood & Cognitive Support: Supports the development and maintenance of healthy cartilage, contributing to overall well-being.
Digestive Health: Contains ingredients that support digestive function.


Sleep Great Sleep Formula by Healthology 😴 🇨🇦
Main Ingredients:
Melatonin
L-Theanine
L-Tryptophan
GABA (Gamma-Aminobutyric Acid)
5-HTP (5-Hydroxytryptophan)
Valerian Root Extract
Skullcap Herb Extract
Loquat Fruit Extract
Benefits:
Sleep: Enhances natural sleep patterns, helping to fall asleep quickly, stay asleep, and achieve deep, restful sleep.
Mood & Cognitive Support: Reduces anxiety and stress, promoting relaxation.
Pain: Improved sleep quality can alleviate pain perception associated with fibromyalgia and arthritis.
Smart Solutions MAGsmart ⚡️💪😴🇨🇦
Main Ingredients:
Malic Acid – Fatigue, pain
Taurine – Mood, nerve support
L-Glutamine – Gut health, energy
Magnesium Bisglycinate – Pain, anxiety, sleep
Inulin – Digestive support (IBS)
Vitamin E – Antioxidant
Potassium (Aspartate) – Energy, muscle support
Vitamin B1/B3/B6/B12, Folic Acid – Mood, energy, brain function
Molybdenum, Selenium – Detox, thyroid function
We hope this information supports you on your wellness journey. If you found it helpful, please share it with a friend. If you enjoy our content, consider contributing to Freedom To Know Wellness to support our ongoing work—you’ll find the link below.
Be Well 💜
Freedom To Know Wellness